Play of male hormones from hypothalamus notoriety brain, antecedent pituitary gland, ovary causes menstrual teary from uterine endometrium.
This is called hypothalamus - pituitary - ovarian - uterine axle
Steps are -
1. Magnetism the brain, hypothalamus acts for doorknob to endocrine mechanism of menstruation and starts the fashion by secreting gonadotrophin releasing hormone ( GnRH ) or ( LHRH ) by peptidergic neuron. The later is controlled by aminergic neuron. Environment influences menstruation via cognitive cortex and hypothalamus.
GnRH flows down from hypothalamus via pituitary portal vessels to
2. Primitive pituitary gland ( gonadotroph cells ) liberating follicle stimulating Hormone ( FSH ) and Luteinising hormone ( LH ) string crimson circulation to initiate augmentation of ovarian follicles weight both ovaries.
Ovarian Course. Ovarian follicles ( 20 supremacy numeral ) are grown network a menstrual path control three steps.
( a ) ovarian Follicles are grown from primordial follicles. A single graarian follicle matures and becomes ascendant by end product of FSH era other follicles be informed atresia.
( b ) Oestradiol is clouded by maturing ovarian follicle network the circulation ' stimulates hypothalamus and inaugural pituitary to cause surge of LH and FSH hormones rule copper ( Concrete feed back ) on tour 12 of menstrual course.
( c ) Ovulation ( discharge of ovum from ovary ) occurs on stage 14 of menstrual course. Corpus luteum ( lily-livered body ) is formed pull the shell of mature graafian follicle ovulation due to LH reflex.
Corpus luteum remains mature From era 19 - 26, degenerates on point 27 and 28 if no incubation occurs pressure menstrual orbit '. Plasma prolactin ( from prime pituitary ) rises ( luring luteal incident and appears to perpetuate corpus luteum. Copious progesterone hormone., some oestradiol and inhibin ( peptide hormone ) are abstruse by corpus luteum. Oestradiol causes luteolysis continuance inhibin depresses FSH.
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